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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AXIN1
All Species:
33.03
Human Site:
Y145
Identified Species:
66.06
UniProt:
O15169
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15169
NP_003493.1
862
95635
Y145
L
K
L
A
R
A
I
Y
R
K
Y
I
L
D
N
Chimpanzee
Pan troglodytes
XP_001152990
821
90810
Y145
L
K
L
A
R
A
I
Y
R
K
Y
I
L
D
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852321
867
95820
Y145
L
K
L
A
K
A
I
Y
R
K
Y
I
L
D
N
Cat
Felis silvestris
Mouse
Mus musculus
O35625
863
96295
Y145
L
K
L
A
R
A
I
Y
R
K
Y
I
L
D
S
Rat
Rattus norvegicus
O70239
827
92266
Y145
L
K
L
A
R
A
I
Y
R
K
Y
I
L
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508740
844
93228
Y141
A
K
A
I
Y
K
R
Y
I
E
N
N
S
I
V
Chicken
Gallus gallus
O42400
841
94913
Y145
L
K
L
A
K
A
I
Y
K
K
Y
I
L
D
N
Frog
Xenopus laevis
Q9YGY0
842
94441
Y145
L
K
L
A
K
A
I
Y
K
K
Y
V
L
D
S
Zebra Danio
Brachydanio rerio
P57094
835
94310
Y148
L
K
L
A
K
A
I
Y
K
K
Y
I
L
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V407
745
81700
H141
P
E
I
P
L
S
P
H
I
F
D
P
M
Q
R
Honey Bee
Apis mellifera
XP_001120373
693
78297
Y105
G
L
E
L
F
R
K
Y
L
D
Q
E
G
R
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781992
855
95982
F148
A
K
L
I
Y
R
R
F
I
K
K
E
G
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
N.A.
86.6
N.A.
87
84.2
N.A.
43.2
73
67.5
64
N.A.
21.8
27.2
N.A.
33
Protein Similarity:
100
95.1
N.A.
91.2
N.A.
91.1
88.1
N.A.
59.4
82.9
79.4
74.8
N.A.
38
42.4
N.A.
50.3
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
13.3
86.6
73.3
86.6
N.A.
0
6.6
N.A.
20
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
33.3
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
67
0
67
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
9
0
0
67
0
% D
% Glu:
0
9
9
0
0
0
0
0
0
9
0
17
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
9
0
9
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
17
0
0
67
0
25
0
0
59
0
9
0
% I
% Lys:
0
84
0
0
34
9
9
0
25
75
9
0
0
0
0
% K
% Leu:
67
9
75
9
9
0
0
0
9
0
0
0
67
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
42
% N
% Pro:
9
0
0
9
0
0
9
0
0
0
0
9
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
17
9
% Q
% Arg:
0
0
0
0
34
17
17
0
42
0
0
0
0
9
9
% R
% Ser:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
25
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
0
84
0
0
67
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _